Homology modeling study of the human interleukin-7 receptor complex

Prediction of the three-dimensional structure of human interleukin-7 by homology modeling.

The three-dimensional structure of human interleukin (IL)-7 has been predicted based on homology to human IL-2, IL-4, granulocyte-macrophage colony stimulating factor and growth hormone. The model has a topology common to other cytokines and displays a unique disulfide pattern. Knowledge of the tertiary structure of IL-7 has implications for analysis of key binding regions, suggestions for muta...

homology modeling of human nmda receptor and studies of the channel symmetry using brownian dynamics simulation

modeling insurance company expenses : the case study of iranian insurance industry

صنعت بیمه به دلیل عرضه محصول منحصر بفرد، در طبقه بندی مالی به عنوان یک صنعت با هزینه های بالا شناخته شده است. رفتار هزینه ها یک معیار مهم برای برای تعیین قدرت مالی شرکت بیمه استو این موضوع به ویژه برای بیمه گذاران و سرمایه گذاران از اهمیت اساسی برخوردار است. این مطالعه هزینه های شرکت های بیمه را در قالب سریهای زمانی پنلی انجام میدهد. تحلیل پنلی کمک برای درک رفتار نا متعارف، پیش بینی هزینه ها، و...

Association study of four polymorphisms in the interleukin-7 receptor alpha gene with multiple sclerosis in Eastern Iran

Objective(s): Multiple sclerosis (MS) is an autoimmune demyelinating disease of the central nervous system (CNS) with unknown etiology. Various genetics and environmental factors contribute to the pathogenesis of the disease. The interleukin-7 receptor alpha chain (IL-7Ra) was identified as the first non-major histocompatibility complex (non-MHC) MS susceptibility locus. In this study we are tr...

IL 7 R ( interleukin 7 receptor )

Review on IL7R, with data on DNA/RNA, on the protein encoded and where the gene is implicated.